Fresh powder on Waddington's slopes.
نویسندگان
چکیده
The Keystone Symposium on Stem Cell Differentiation and Dedifferentiation attracted nearly 500 participants affiliated with academia, the biotechnology industry, scientific publishing and clinical practice. This broad group examined current advances in stem-cell biology, with a particular focus on induced pluripotent stem cells, and discussed both their potential and limitations in therapeutic applications.
منابع مشابه
Bistability, Bifurcations, and Waddington's Epigenetic Landscape
Waddington's epigenetic landscape is probably the most famous and most powerful metaphor in developmental biology. Cells, represented by balls, roll downhill through a landscape of bifurcating valleys. Each new valley represents a possible cell fate and the ridges between the valleys maintain the cell fate once it has been chosen. Here I examine models of two important developmental processes -...
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The paper " Une théorie dynamique de la morphgenèse " , written by René Thom in 1966 and appeared in 1967 in Towards a theoretical Biology I, published by Conrad Hal Waddington, can be considered as the princeps paper of the catastrophe theory. In this paper Thom declares that embryology and, in particular, Waddington's notions of epigenetic landscape and chreod have been one of his sources in ...
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ورودعنوان ژورنال:
- EMBO reports
دوره 11 7 شماره
صفحات -
تاریخ انتشار 2010